http://jnnp.bmj.com/content/87/10/1127.long I question this because I take 5 mgs of Melatonin as needed. It has not improved my migraines at all. I've taken 100 mgs of Amitriptyline; it didn't do anything. I worry that, if chosen for a migraine study, I will be placed on the placebo, but that's a chance I am willing to … Continue reading Randomized Clinical Trial Comparing Melatonin 3 mg, Amitriptyline 25 mg, and Placebo For Migraine Prevention