I’m a rare success story with Cymbalta, at a very high dose of 360 mgs. I took it accidentally, but it helped so much and my doctor had zero issues with the dosing. Unfortunately, once it stopped working, I could no longer tolerate even the smallest dose. 😦 I have no idea what it’s like to be pain-free.
Savella has been on the market for years, so I don’t, by any means, consider it “new”. I don’t know how comfortable I’d be with Xyrem, but we’ll see what happens once it’s FDA approved. Sadly, I am afraid it will be abused by people who do not suffer from Fibromyalgia or any form of chronic pain, and that is worrisome to me. Still, I’d be happy if it is able to help some of us.